Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.570 | AlteredExpression | disease | BEFREE | Serum myostatin levels were higher in CHF patients than in controls. | 31056368 | 2019 | ||||
|
0.570 | AlteredExpression | disease | BEFREE | Although there are disparities in pathophysiology and epidemiology between male and female patients with HF, it remains unclear whether there is gender difference in myostatin expression and whether it is associated with weight loss in HF patients. | 28465115 | 2017 | ||||
|
0.570 | AlteredExpression | disease | BEFREE | Myostatin expression is also found in heart in a much less extent, but it can be upregulated in pathological conditions, such as heart failure. | 29069231 | 2017 | ||||
|
0.570 | Biomarker | disease | BEFREE | Circulating and local myostatin is elevated in chronic heart failure and poses a major player in cardiac cachexia. | 24680839 | 2014 | ||||
|
0.570 | AlteredExpression | disease | BEFREE | In late-stage CHF, exercise training led to a 36% reduction of the mRNA and a 23% decrease of the myostatin protein compared to baseline. | 21450574 | 2012 | ||||
|
0.570 | Biomarker | disease | BEFREE | We describe the development of the first ELISA for myostatin immunoreactivity and its validation during recompensating therapy for CHF. | 22561185 | 2012 | ||||
|
0.570 | Biomarker | disease | BEFREE | To therapeutically influence skeletal muscle wasting, direct inhibition of myostatin was shown to positively impact skeletal muscle mass in heart failure, suggesting a promising strategy for the treatment of cardiac cachexia in the future. | 21421824 | 2011 | ||||
|
0.570 | Biomarker | disease | CTD_human | However, the expression of myostatin in chronic heart failure resulting from volume-overload and after treatment with beta-blockers is little known. | 16968467 | 2006 | ||||
|
0.570 | Biomarker | disease | RGD | However, the expression of myostatin in chronic heart failure resulting from volume-overload and after treatment with beta-blockers is little known. | 16968467 | 2006 |